Science & regulatory ---
Choline is a vital nutrient, essential for optimal health. It is backed by scientific research - yet it remains under-consumed by the majority of people.
We are committed to science-based nutrition. This page presents the scientific and regulatory background that supports the use of Cholife®. Choline is a vital nutrition with scientifically validated health benefits.
Both the European Food Safety Authority (EFSA) and the US Food & Drug Administration (US FDA) have thoroughly investigated the use of choline.
EFSA has approved 3 health claims, they state that choline:
– Contributes to normal lipid metabolism
– Contributes to the maintenance of normal liver function
– Contributes to normal homocysteine metabolism
A new application for a health claim related to choline and contribution to normal liver function of the foetus and exclusively breastfed children is currently under investigation. A cause and effect relationship has been established already. More information will follow.
Both EFSA and the US FDA have published dietary reference values on the daily intake of choline:
Downloads
Articles
- EFSA scientific opinion on health claims related to choline
- EFSA scientific opinion on dietary reference values for choline
- EFSA scientific opinion on choline and contribution to normal liver function of the foetus and exclusively breastfed infants
- Regulation (EC) No 1924/2006 on nutrition and health claims made on foods
- Regulation (EC) No 2016/2017 regards the specific compositional and information requirements for infant formula and follow on formula
— Brain health
Choline is required for the synthesis of acetylcholine, a neurotransmitter that acts as a messenger, allowing messages to be faster transferred in the brain. Acetylcholine circulates signals to the right part of our body and is involved in memory maturation, control of muscles and other functions, such as learning, alertness and attention.
— Heart health
Choline regulates homocysteine reduction. Elevated levels of homocysteine are known to increase the risk of cardiovascular disease and thrombosis. Choline ensures a good heart condition due to the conversion of homocysteine in methionine.
— Liver health & lipid metabolism
Fats and cholesterol accumulate in our liver in the form of lipoproteins. Choline transports these lipoproteins out of the liver, supporting normal lipid metabolism and preventing fatty liver disease.
— Sport performance
During exercise, it is important that brain and muscles communicate well. As choline is the precursor of acetylcholine, it helps to transmit signals from brain to muscles, allowing our muscles to activate.
— Pre- and post-natal health
Choline is an essential building block for cell membranes. During pregnancy and lactation, mothers require sufficient choline intake to ensure proper fetal and child brain development. Hence, baby food is mostly fortified with choline.
